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Peptide record

TPDB64438

PN287 (SEQ ID NO: 87) Cell-penetrating Peptides standard
8 amino acids
Basic Information
3D PDB MODEL
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TPDB64438
PN287 (SEQ ID NO: 87)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 8-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Maleimide addition
Sequence
WRFKWRFK-NH2
Physicochemical Analysis
C64H88N18O9
ANDCEQGHILMPSTYV
RKFW
1253.52
12.42
4
0
4
+4
-2.36
-1.625
0.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
11000
877.53
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
2
K
0
M
2
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 2 M: 0 F: 2 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
8
C64H88N18O9
1253.52
12.42
+4
-2.36
-1.625
Amidation
L
Linear
Maleimide addition
N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCSCCSCC
Additional Detail Fields 1 fields
CCSCCSCC