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Peptide record

TPDB64428

PF222 Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB64428
PF222
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation Chemical: Magnetic nanoparticles (MNPs) N-terminal: Stearylation
Sequence
WLRLLWKKWFLKL-NH2
Physicochemical Analysis
C96H144N22O14
ANDCEQGHIMPSTYV
L
1830.34
11.73
4
0
9
+4
-5.70
0.223
150.00
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
16500
901.47
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
5
L
3
K
0
M
1
F
0
P
0
S
0
T
3
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 5 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 3 Y: 0 V: 0
Chemical Descriptors
13
C96H144N22O14
1830.34
11.73
+4
-5.70
0.223
Amidation
Magnetic nanoparticles (MNPs)
L
Linear
Stearylation
N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U-87 Mg-Luc2, HeLa Pulc 705

Assay & Model

Mice
Mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Plasmid (pGL3, splicing correcting oligonucleotides (SCO), and small interfering RNA (siRNA)
In vitro
CCSSCTTCCCC
Additional Detail Fields 1 fields
CCSSCTTCCCC