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Peptide record

TPDB64419

PF21 Cell-penetrating Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB64419
PF21
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 19-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD-MOD, CPPsite3.0, Peptipedia, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Stearylation
Sequence
WLKLLKKWLKLWKKLLKLW-NH2
Physicochemical Analysis
C134H214N30O20
ARNDCEQGHIMFPSTYV
L
2565.36
11.29
7
0
12
+7
-4.95
-0.026
164.21
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
22000
857.58
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
8
L
7
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 8 K: 7 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
19
C134H214N30O20
2565.36
11.29
+7
-4.95
-0.026
Amidation
L
Amphipathic
Linear
Stearylation
N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HEK-293 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Nucleic acid (Plasmid DNA)
More efficient than PepFect 3
In vitro
CHHHHHHHHHHHTTSTTCC
Additional Detail Fields 1 fields
CHHHHHHHHHHHTTSTTCC