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Peptide record

TPDB64413

CPP6-1 Cell-penetrating Peptides standard
6 amino acids
Basic Information
3D PDB MODEL
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TPDB64413
CPP6-1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 6-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
WKLPVM
Physicochemical Analysis
C38H60N8O7S1
ARNDCEQGHIFSTY
LKMPWV
773.00
10.10
1
0
4
+1
-1.13
0.583
113.33
Mammalian: 2.8 hour Yeast: 3 min E.coli: 2 min
5500
711.51
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
1
L
1
K
1
M
0
F
1
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 1 K: 1 M: 1 F: 0 P: 1 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
6
C38H60N8O7S1
773.00
10.10
+1
-1.13
0.583
Free
L
Cationic
Linear
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Caco-2 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic
Synthetic
Gemcitabine drug
9 % of the Gem-CPP6-1 conjugate was found in the basolateral chamber
In vitro