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Peptide record

TPDB64359

Integrin Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB64359
Integrin
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
VTVLALGALAGVGVG
Physicochemical Analysis
C59H105N15O17
RNDCEQHIKMFPSWY
GV
1296.57
6.02
0
0
10
-0
-1.73
2.087
175.33
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
4
G
0
H
0
I
3
L
0
K
0
M
0
F
0
P
0
S
1
T
0
W
0
Y
4
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 4 H: 0 I: 0 L: 3 K: 0 M: 0 F: 0 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 4
Chemical Descriptors
15
C59H105N15O17
1296.57
6.02
-0
-1.73
2.087
Free
L
Linear
Free
N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, A549,Caco-2, THP-1, and RAW264.7 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Salmonella phage selz
Late Endosomes/Lysosomes
selzIntergrin showed a significantly higher uptake number of phages than WT selz in A549 cells.
In vitro
CCTTTGGGSSSCC
Additional Detail Fields 1 fields
CCTTTGGGSSSCC