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Peptide record

TPDB64356

V31KT (AF + Antp) Cell-penetrating Peptides standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB64356
V31KT (AF + Antp)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 31-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: GGGG as a Linker
Sequence
VTDFGVFVEIGGGGSRQIKIWFQNRRMKWKK
Physicochemical Analysis
C169H263N49O41S1
ACHLPY
G
3669.31
11.53
7
2
12
+5
3.50
-0.500
65.81
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
11000
299.78
5
Residue Composition
number
0
A
3
R
1
N
1
D
0
C
1
E
2
Q
5
G
0
H
3
I
0
L
4
K
1
M
3
F
0
P
1
S
1
T
2
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 1 C: 0 E: 1 Q: 2 G: 5 H: 0 I: 3 L: 0 K: 4 M: 1 F: 3 P: 0 S: 1 T: 1 W: 2 Y: 0 V: 3
Chemical Descriptors
31
C169H263N49O41S1
3669.31
11.53
+5
3.50
-0.500
Free
GGGG as a Linker
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)NCC(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Bt474 Cells S. Aureus, Mrsa, And B. Cereus

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
Amyloidogenic fragment (AF) at N terminal
In vitro
CCTTTCSSCSSSCSSCCCSCCCC
Additional Detail Fields 1 fields
CCTTTCSSCSSSCSSCCCSCCCC