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Peptide record

TPDB64351

Scp01-b Cell-penetrating Peptides standard
41 amino acids
Basic Information
3D PDB MODEL
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TPDB64351
Scp01-b
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 41-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with FITC
Sequence
VSRRRRRRGGRRRRGGGSYARVRRRGPRRGYARVRRRGPRR
Physicochemical Analysis
C203H369N107O46
NDCEQHILKMFTW
R
5044.85
13.20
22
0
7
+22
17.05
-2.278
26.10
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
2980
59.07
4
Residue Composition
number
2
A
22
R
0
N
0
D
0
C
0
E
0
Q
8
G
0
H
0
I
0
L
0
K
0
M
0
F
2
P
2
S
0
T
0
W
2
Y
3
V
Amino Acid Distribution
A: 2 R: 22 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 8 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 2 S: 2 T: 0 W: 0 Y: 2 V: 3
Chemical Descriptors
41
C203H369N107O46
5044.85
13.20
+22
17.05
-2.278
Free
L
Linear
Conjugated with FITC
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Caski , A2780, Mg63, Hsc-T10

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
FITC dye and pcDNA3.1-GFP
Scp01-b has higher penetration efficiency than RP010 and MT23, but weaker than hPP10 and TAT
Lipid-raft mediated endocytosis
In vitro
CCSGGGGGCCC
Additional Detail Fields 1 fields
CCSGGGGGCCC