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Peptide record

TPDB64332

AcPHF6YKR9 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB64332
AcPHF6YKR9
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Acetylation
Sequence
Ac-VQIVKKRRRRRRRRR-NH2
Physicochemical Analysis
C87H171N45O17
ANDCEGHLMFPSTWY
R
2119.61
13.30
11
0
3
+11
9.68
-2.593
64.67
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
1
Residue Composition
number
0
A
9
R
0
N
0
D
0
C
0
E
1
Q
0
G
0
H
1
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 9 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
15
C87H171N45O17
2119.61
13.30
+11
9.68
-2.593
Amidation
L
Linear
Acetylation
N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Ht-22 , HeLa And Hek293 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Rhodamine-labelled at N terminus
No ThS staining in cells treated only with vehicle (control) or in cells treated with AcPHF6YKR9
In vitro
CCCCHHHHTTCSCCC
Additional Detail Fields 1 fields
CCCCHHHHTTCSCCC