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Peptide record

TPDB64300

DPT-C9h Cell-penetrating Peptides standard
30 amino acids
Basic Information
3D PDB MODEL
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TPDB64300
DPT-C9h
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 30-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
VKKKKIKREIKIYVETLDDIFEQWAHSEDL
Physicochemical Analysis
C170H273N43O49
NCGMP
K
3703.30
7.68
8
7
12
+0
14.02
-0.807
100.67
Mammalian: 100 hour Yeast: >20 hour E.coli: >10 hour
6990
188.75
4
Residue Composition
number
1
A
1
R
0
N
3
D
0
C
4
E
1
Q
0
G
1
H
4
I
2
L
6
K
0
M
1
F
0
P
1
S
1
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 3 C: 0 E: 4 Q: 1 G: 0 H: 1 I: 4 L: 2 K: 6 M: 0 F: 1 P: 0 S: 1 T: 1 W: 1 Y: 1 V: 2
Chemical Descriptors
30
C170H273N43O49
3703.30
7.68
+0
14.02
-0.807
Free
L
Cationic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Hbcx-3, Hbcx-12A, Hbcx-17

Assay & Model

breast cancer xenograft model (Nude Mice)
breast cancer xenograft model (Nude Mice)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Cy5-labeled
In vitro and in vivo
CCSTHHHHHHHHSCC
Additional Detail Fields 1 fields
CCSTHHHHHHHHSCC