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Peptide record

TPDB64269

FLR (FGF2B-LK15-8R) Cell-penetrating Peptides standard
39 amino acids
Basic Information
3D PDB MODEL
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TPDB64269
FLR (FGF2B-LK15-8R)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 39-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: Dextran-magnetic nanoparticles (MNPs)
Sequence
TYRSRKYTSWYVALKRKLLKLLLKLLLKLLKRRRRRRRR
Physicochemical Analysis
C234H414N80O47
NDCEQGHIMFP
RL
5100.37
12.65
18
0
17
+18
5.45
-0.944
120.00
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
9970
195.48
7
Residue Composition
number
1
A
11
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
11
L
7
K
0
M
0
F
0
P
2
S
2
T
1
W
3
Y
1
V
Amino Acid Distribution
A: 1 R: 11 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 11 K: 7 M: 0 F: 0 P: 0 S: 2 T: 2 W: 1 Y: 3 V: 1
Chemical Descriptors
39
C234H414N80O47
5100.37
12.65
+18
5.45
-0.944
Free
Dextran-magnetic nanoparticles (MNPs)
L
Linear
Free
N[C@@H]([C@@H](C)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Nih3T3 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
Rh-pDNA pGLuc
Nucleus
FLR-DNA-MNP nanocomplex transfection was significantly enhanced (almost 2-fold) by the presence of a magnetic field during 1 h transfection (2.09 ± 0.45 × 107 RLU with a magnet compared to 1.13 ± 0.6 × 107 RLU without a magnet).
More than one endocytosis pathways
In vitro
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHTTSCCC
Additional Detail Fields 1 fields
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHTTSCCC