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Peptide record

TPDB64256

TVS Cell-penetrating Peptides standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB64256
TVS
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 7-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
TVSRPAF
Physicochemical Analysis
C35H56N10O10
NDCEQGHILKMWY
ARFPSTV
776.89
11.05
1
0
3
+1
0.30
0.171
55.71
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
2
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
1
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
7
C35H56N10O10
776.89
11.05
+1
0.30
0.171
Free
L
Cyclic
Free
N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Caco-2 Cells

Assay & Model

Male ICR mice (mouse intestinal epithelium)
Male ICR mice (mouse intestinal epithelium)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Cyclic L
Phage Display
M13 phage
The amounts of TVS-phage was 18.6-fold greater than that of control phage at 30 min
In vitro and in vivo
CCSSCCC
Additional Detail Fields 1 fields
CCSSCCC