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Peptide record

TPDB64253

TAT-ETD-IA Cell-penetrating Peptides standard
56 amino acids
Basic Information
3D PDB MODEL
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TPDB64253
TAT-ETD-IA
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 56-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Conjugated with FLAG epitope
Sequence
TTTATTDELKTVTKDRMEDIKILIAEPSPTHIHKETTSATSSPGRKKRRQRRRPPQ
Physicochemical Analysis
C270H465N89O88S1
NCFWY
T
6398.27
11.07
15
7
11
+6
27.75
-1.339
52.32
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
17
Residue Composition
number
3
A
7
R
0
N
3
D
0
C
4
E
2
Q
1
G
2
H
4
I
2
L
6
K
1
M
0
F
5
P
4
S
11
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 7 N: 0 D: 3 C: 0 E: 4 Q: 2 G: 1 H: 2 I: 4 L: 2 K: 6 M: 1 F: 0 P: 5 S: 4 T: 11 W: 0 Y: 0 V: 1
Chemical Descriptors
56
C270H465N89O88S1
6398.27
11.07
+6
27.75
-1.339
Conjugated with FLAG epitope
L
Cationic
Linear
Free
N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Huh7, HeLa, Hepg2

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Chimeric
ETD variants
Nuclear
Detected inside the cells 2 h post-transduction
In vitro
CCSSSCC
Additional Detail Fields 1 fields
CCSSSCC