Back to search

Peptide record

TPDB64203

Vpr55-91 Cell-penetrating Peptides standard
37 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB64203
Vpr55-91
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 37-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
TGVEALIRILQQLLFIHFRIGCRHSRIGIIQQRRTRN
Physicochemical Analysis
C195H331N67O48S1
DKMPWY
RI
4414.25
12.53
9
1
15
+6
5.78
-0.041
126.49
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
9
Residue Composition
number
1
A
7
R
1
N
0
D
1
C
1
E
4
Q
3
G
2
H
7
I
4
L
0
K
0
M
2
F
0
P
1
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 7 N: 1 D: 0 C: 1 E: 1 Q: 4 G: 3 H: 2 I: 7 L: 4 K: 0 M: 0 F: 2 P: 0 S: 1 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
37
C195H331N67O48S1
4414.25
12.53
+6
5.78
-0.041
Free
L
Cationic
Linear
Free
N[C@@H]([C@@H](C)O)C(=O)NCC(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)NCC(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HEGP2, CHO Cells , MO-DC Cells , HLA-A0201 Negative CHO-K1 Cells

Assay & Model

HLA-A*0201 transgenic mice
HLA-A*0201 transgenic mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
avidin-β-Gal , BSA-FITC , DTAF-MART-1 antigen
Cytosol
Endocytosis
In vitro and in vivo
CTHHHHHHHHHHHHHSSTTCCSCCCSSCCCCCCCC
Additional Detail Fields 1 fields
CTHHHHHHHHHHHHHSSTTCCSCCCSSCCCCCCCC