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Peptide record

TPDB64193

Angiopep-1 Blood-Brain Barrier Cell-penetrating Peptides standard
19 amino acids
Basic Information
3D PDB MODEL
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TPDB64193
Angiopep-1
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
B3Pred BBPpredict Peptipedia CPPsite3.0
standard
No
A 19-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from B3Pred, BBPpredict, Peptipedia, and other sources, with an available 3D structural model.
Sequence
TFFYGGCRGKRNNFKTEEY
Physicochemical Analysis
C104H149N29O30S1
ADQHILMPSWV
GF
2317.56
9.53
4
2
5
+2
3.28
-1.321
0.00
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
2980
128.58
7
Residue Composition
number
0
A
2
R
2
N
0
D
1
C
2
E
0
Q
3
G
0
H
0
I
0
L
2
K
0
M
3
F
0
P
0
S
2
T
0
W
2
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 2 D: 0 C: 1 E: 2 Q: 0 G: 3 H: 0 I: 0 L: 0 K: 2 M: 0 F: 3 P: 0 S: 0 T: 2 W: 0 Y: 2 V: 0
Chemical Descriptors
19
C104H149N29O30S1
2317.56
9.53
+2
3.28
-1.321
Linear
Similarity
Thr-Phe-Phe-Tyr-Gly-Gly-Cys-Arg-Gly-Lys-Arg-Asn-Asn-Phe-Lys-Thr-Glu-Glu-Tyr
Evidence Records 5 records
Evidence 1 Activity

Activity

Blood-Brain Barrier
37.28%

Assay & Model

Capillary depletion
Origin/Source
% capillary

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Direct iodination
Evidence 2 Activity

Activity

Blood-Brain Barrier
62.72%

Assay & Model

Capillary depletion
Origin/Source
% capillary

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Direct iodination
Evidence 3 Activity

Activity

Blood-Brain Barrier
0.3537 ml/g

Assay & Model

Capillary deplition in situ b p
Origin/Source
CD(brain/perfusate)

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Direct iodination
Evidence 4 Activity

Activity

Blood-Brain Barrier
0.1341 ml/g

Assay & Model

Capillary deplition in situ b p
Origin/Source
CD(capillary/perfusate)

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Direct iodination
Evidence 5 Activity

Activity

Blood-Brain Barrier
0.2256 ml/g

Assay & Model

Capillary deplition in situ b p
Origin/Source
CD(parenchyma/perfusate)

Source & Reference

NA
B3Pdb

Other

Chemically synthesized
Direct iodination