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Peptide record

TPDB64191

LadD64–95 Cell-penetrating Peptides standard
31 amino acids
Basic Information
3D PDB MODEL
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TPDB64191
LadD64–95
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 31-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Biotinylation
Sequence
TERAKRRDRRRRSVCHARTWFCFRKYDVRRS
Physicochemical Analysis
C171H281N69O43S2
NQGILMP
R
4055.67
12.17
14
3
8
+10
11.14
-1.729
25.16
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
7115
175.43
7
Residue Composition
number
2
A
11
R
0
N
2
D
2
C
1
E
0
Q
0
G
1
H
0
I
0
L
2
K
0
M
2
F
0
P
2
S
2
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 11 N: 0 D: 2 C: 2 E: 1 Q: 0 G: 0 H: 1 I: 0 L: 0 K: 2 M: 0 F: 2 P: 0 S: 2 T: 2 W: 1 Y: 1 V: 2
Chemical Descriptors
31
C171H281N69O43S2
4055.67
12.17
+10
11.14
-1.729
Free
L
Cationic
Linear
Biotinylation
N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CS)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U87G Cells And Dermal Human Primary Fibroblasts (Dhf) S. Agalactiae Mutant Nem 316 Δdlta Strain

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Streptavidin–HRP
Wild-type LadD and adD have similar penetrating properties to the HIV-1 Tat peptide in U87G and DHFs
In vitro
CCCCCHHHHTTTTTSSSCCCCCTTCCTTCC
Additional Detail Fields 1 fields
CCCCCHHHHTTTTTSSSCCCCCTTCCTTCC