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Peptide record

TPDB64190

adD64–78 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB64190
adD64–78
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Biotinylation
Sequence
TERAKRRDRRRRSVC
Physicochemical Analysis
C75H141N37O22S1
NQGHILMFPWY
R
1945.24
12.28
8
2
2
+6
9.84
-2.360
26.00
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
7
R
0
N
1
D
1
C
1
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
0
F
0
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 7 N: 0 D: 1 C: 1 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 0 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
15
C75H141N37O22S1
1945.24
12.28
+6
9.84
-2.360
Free
L
Cationic
Linear
Biotinylation
N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U87G Cells And Dermal Human Primary Fibroblasts (Dhf) S. Agalactiae Mutant Nem 316 Δdlta Strain

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Streptavidin–HRP
Wild-type LadD and adD have similar penetrating properties to the HIV-1 Tat peptide in U87G and DHFs
In vitro
CCCCCHHHHHHSCCC
Additional Detail Fields 1 fields
CCCCCHHHHHHSCCC