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Peptide record

TPDB64181

IL-13p Cell-penetrating Peptides standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB64181
IL-13p
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 36-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Sequence
TAMRAVDKLLLHLKKLFREGQFNRNFESIIICRDRT
Physicochemical Analysis
C192H319N59O51S2
PWY
RL
4334.13
10.78
9
4
15
+4
8.46
-0.317
100.28
Mammalian: 7.2 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
7
Residue Composition
number
2
A
5
R
2
N
2
D
1
C
2
E
1
Q
1
G
1
H
3
I
5
L
3
K
1
M
3
F
0
P
1
S
2
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 5 N: 2 D: 2 C: 1 E: 2 Q: 1 G: 1 H: 1 I: 3 L: 5 K: 3 M: 1 F: 3 P: 0 S: 1 T: 2 W: 0 Y: 0 V: 1
Chemical Descriptors
36
C192H319N59O51S2
4334.13
10.78
+4
8.46
-0.317
Free
L
Linear
Free
N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U87 cells and HUVECs

Assay & Model

BALB/c nude mice
BALB/c nude mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (Coumarin-6 and DiR)
Significantly enhanced
In vitro and in vivo
CTTSCTHHHHSSTTTTTSSCCCCCTTTTCCCCTTC
Additional Detail Fields 1 fields
CTTSCTHHHHSSTTTTTSSCCCCCTTTTCCCCTTC