Back to search

Peptide record

TPDB64130

DPV10 Cell-penetrating Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB64130
DPV10
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 14-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Cys addition
Sequence
SRRARRSPRHLGSG
Physicochemical Analysis
C63H113N31O18
NDCEQIKMFTWYV
R
1592.79
13.00
6
0
2
+5
5.14
-1.779
35.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
1
A
5
R
0
N
0
D
0
C
0
E
0
Q
2
G
1
H
0
I
1
L
0
K
0
M
0
F
1
P
3
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 1 I: 0 L: 1 K: 0 M: 0 F: 0 P: 1 S: 3 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C63H113N31O18
1592.79
13.00
+5
5.14
-1.779
Free
L
Linear
Cys addition
N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CO)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, HCT116, HL-60, K562, Molt4, NIH-3T3 and primary hepatocyte cultures

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Protein (PO and IgG)
Nucleus
Energy-dependent endocytic process involving cell membrane lipid rafts
In vitro
CCCCCCCCCCSCC
Additional Detail Fields 1 fields
CCCCCCCCCCSCC