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Peptide record

TPDB64122

Engrailed-2 Blood-Brain Barrier Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB64122
Engrailed-2
Blood-Brain Barrier Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
BBPpredict CPPsite3.0
standard
No
A 16-aa standard natural multi-activity (Blood-Brain Barrier and Cell-penetrating Peptides) peptide sequence curated from BBPpredict and CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with Cyanine5.5 (Cy5.5)
Sequence
SQIKIWFQNKRAKIKK
Physicochemical Analysis
C94H158N28O21
DCEGHLMPTYV
K
2016.46
11.85
6
0
6
+6
3.39
-1.131
79.38
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
5500
272.75
4
Residue Composition
number
1
A
1
R
1
N
0
D
0
C
0
E
2
Q
0
G
0
H
3
I
0
L
5
K
0
M
1
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 3 L: 0 K: 5 M: 0 F: 1 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
16
C94H158N28O21
2016.46
11.85
+6
3.39
-1.131
Free
L
Cationic
Linear
Conjugated with Cyanine5.5 (Cy5.5)
N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Primary Human Astrocytes

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Cy5.5 dye
Highest fluorescence level inside the spheroids
In vitro
CCSSSCCSCCSCCCC
Additional Detail Fields 1 fields
CCSSSCCSCCSCCCC