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Peptide record

TPDB64086

PN61 (SEQ ID NO: 56) Cell-penetrating Peptides standard
38 amino acids
Basic Information
3D PDB MODEL
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TPDB64086
PN61 (SEQ ID NO: 56)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 38-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation
Sequence
SGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGC-NH2
Physicochemical Analysis
C172H304N68O45S1
NDEIMWY
RG
4076.79
12.81
13
0
10
+12
10.20
-0.958
56.58
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
7
Residue Composition
number
4
A
7
R
0
N
0
D
1
C
0
E
2
Q
7
G
1
H
0
I
3
L
5
K
0
M
1
F
1
P
3
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 7 N: 0 D: 0 C: 1 E: 0 Q: 2 G: 7 H: 1 I: 0 L: 3 K: 5 M: 0 F: 1 P: 1 S: 3 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
38
C172H304N68O45S1
4076.79
12.81
+12
10.20
-0.958
Amidation
L
Linear
Free
N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)N[C@@H](CS)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCSCCGGGCCCCSCCCCCCCCCCCCCGGGSCTTTSCC
Additional Detail Fields 1 fields
CCSCCGGGCCCCSCCCCCCCCCCCCCGGGSCTTTSCC