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Peptide record

TPDB64085

PN279 (SEQ ID NO: 55) Cell-penetrating Peptides standard
37 amino acids
Basic Information
3D PDB MODEL
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TPDB64085
PN279 (SEQ ID NO: 55)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia
standard
No
A 37-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Maleimide adition
Sequence
SGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKG-NH2
Physicochemical Analysis
C169H299N67O44
NDCEIMWY
RG
3973.66
13.18
13
0
10
+12
10.44
-1.051
58.11
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
6
Residue Composition
number
4
A
7
R
0
N
0
D
0
C
0
E
2
Q
7
G
1
H
0
I
3
L
5
K
0
M
1
F
1
P
3
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 4 R: 7 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 7 H: 1 I: 0 L: 3 K: 5 M: 0 F: 1 P: 1 S: 3 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
37
C169H299N67O44
3973.66
13.18
+12
10.44
-1.051
Amidation
L
Linear
Maleimide adition
N[C@@H](CO)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)NCC(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

9 L/LacZ cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCCGGGCCCCCCCCCSCCCCCSCSSCGGGSSSGGGC
Additional Detail Fields 1 fields
CCCGGGCCCCCCCCCSCCCCCSCSSCGGGSSSGGGC