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Peptide record

TPDB64080

Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB64080
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 12-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
SFRRRRSGKRKS
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C62H113N29O16
ANDCEQHILMPTWYV
R
1520.76
13.01
7
0
1
+7
7.67
-2.525
0.00
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
0
0.00
3
Residue Composition
number
0
A
5
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
2
K
0
M
1
F
0
P
3
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 2 M: 0 F: 1 P: 0 S: 3 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
12 main sequence record
C62H113N29O16 sequence-only estimate (linear, free termini)
1520.76 sequence-only estimate (linear, free termini)
13.01 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
7.67 sequence-only estimate (linear, free termini)
-2.525 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.