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Peptide record

TPDB64074

Cell-penetrating Peptides standard
35 amino acids
Basic Information
3D PDB MODEL
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TPDB64074
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 35-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
SEEIITPVYCTGVSAQVQKGLRKRLRKFRNKIKEK
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C181H312N56O50S1
DHMW
K
4104.87
10.84
10
3
11
+7
2.82
-0.809
83.43
Mammalian: 1.9 hour Yeast: >20 hour E.coli: >10 hour
1490
0.36
9
Residue Composition
number
1
A
4
R
1
N
0
D
1
C
3
E
2
Q
2
G
0
H
3
I
2
L
6
K
0
M
1
F
1
P
2
S
2
T
0
W
1
Y
3
V
Amino Acid Distribution
A: 1 R: 4 N: 1 D: 0 C: 1 E: 3 Q: 2 G: 2 H: 0 I: 3 L: 2 K: 6 M: 0 F: 1 P: 1 S: 2 T: 2 W: 0 Y: 1 V: 3
Chemical Descriptors
35 main sequence record
C181H312N56O50S1 sequence-only estimate (linear, free termini)
4104.87 sequence-only estimate (linear, free termini)
10.84 sequence-only estimate (linear, free termini)
+7 sequence-only estimate (linear, free termini)
2.82 sequence-only estimate (linear, free termini)
-0.809 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.