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Peptide record

TPDB64063

RY4 Cell-penetrating Peptides standard
5 amino acids
Basic Information
3D PDB MODEL
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TPDB64063
RY4
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 5-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RYIRS
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C30H51N11O8
ANDCEQGHLKMFPTWV
R
693.80
11.16
2
0
2
+2
5.69
-1.320
78.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
2.15
2
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
0
L
0
K
0
M
0
F
0
P
1
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 0 K: 0 M: 0 F: 0 P: 0 S: 1 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
5 main sequence record
C30H51N11O8 sequence-only estimate (linear, free termini)
693.80 sequence-only estimate (linear, free termini)
11.16 sequence-only estimate (linear, free termini)
+2 sequence-only estimate (linear, free termini)
5.69 sequence-only estimate (linear, free termini)
-1.320 sequence-only estimate (linear, free termini)
Free Activity
L Activity
Cationic Activity
Linear Activity
Free Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear L Cationic
Synthetic
pHPMA polymer
Cytoplasm
Do not penetrate cells better than the control polymer
In vitro