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Peptide record

TPDB64058

(RX)8B Cell-penetrating Peptides modified_plain modified
17 amino acids
Basic Information
3D PDB MODEL
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Sequence-matched coordinates; source-recorded chemical modifications are not verified in this model.

TPDB64058
(RX)8B
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 17-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: X, 6-aminohexanoic acid (Ahx) and B, Beta-Alanine
Sequence
RXRXRXRXRXRXRXRXB

Source notation is retained verbatim; residue identity and the source-provided length have not been independently validated.

Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
17 main sequence record
X, 6-aminohexanoic acid (Ahx) and B, Beta-Alanine Activity
Modified Activity
Cationic Activity
Linear Activity
Evidence Records 3 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MCF7 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified Cationic
Synthetic
Nucleic acid [PPMOs targeting translation initiation site of p53 mRNA (M1)]
In vitro
Evidence 2 Activity

Activity

Cell-penetrating Peptides

Target

MCF7 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Non-natural residues Linear Modified Cationic
Synthetic
Nucleic acid [PPMOs targeting splice acceptor site of exon 10 (E10SA)]
In vitro
Evidence 3 Activity

Activity

Cell-penetrating Peptides

Target

MCF7 cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Non-natural residues Linear Modified Cationic
Synthetic
Nucleic acid [PPMOs targeting the coding region within exon 10
In vitro