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Peptide record

TPDB64046

Pip6a Cell-penetrating Peptides modified_plain modified
22 amino acids
Basic Information
3D PDB MODEL
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Sequence-matched coordinates; source-recorded chemical modifications are not verified in this model.

TPDB64046
Pip6a
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 22-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: B, Beta-Alanine and X, 6-aminohexanoic acid (Ahx) N-terminal: Acetylation
Sequence
Ac-RXRRBRRXRYQFLIRXRBRXRB

Source notation is retained verbatim; residue identity and the source-provided length have not been independently validated.

Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
22 main sequence record
Free Activity
B, Beta-Alanine and X, 6-aminohexanoic acid (Ahx) Activity
Modified Activity
Linear Activity
Acetylation Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Murine H2k mdx myoblasts and C2C12 cells

Assay & Model

1- to 2-day-old newborn wild-type C57BL/6 J mice
1- to 2-day-old newborn wild-type C57BL/6 J mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Linear Modified
Synthetic
Nucleic acid [phosphorodiamidate morpholino oligomers (PMO)]
Vesicles
Dose dependent uptake
Energy and caveolae-mediated endocytosis
In vitro and in vivo