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Peptide record

TPDB64010

ARF(2-14) scr Cell-penetrating Peptides standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB64010
ARF(2-14) scr
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 13-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugation with fluorescein
Sequence
RVRILARFLRTRV-NH2
Physicochemical Analysis
C74H134N28O15
NDCEQGHKMPSWY
R
1656.06
13.00
5
0
7
+5
1.60
0.146
142.31
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
5
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
2
L
0
K
0
M
1
F
0
P
0
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 5 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 0 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
13
C74H134N28O15
1656.06
13.00
+5
1.60
0.146
Amidation
L
Linear
Conjugation with fluorescein
N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

MCF-7 and MDA MB 231

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Fluorophore (fluorescein)
Lower than ARF (2-14)
In vitro
CCGGGHHHHTSCC
Additional Detail Fields 1 fields
CCGGGHHHHTSCC