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Peptide record

TPDB64008

PN316 (SEQ ID NO: 92) Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB64008
PN316 (SEQ ID NO: 92)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Maleimide addition
Sequence
RVIRWFQNKRSKDKK-NH2
Physicochemical Analysis
C89H149N31O21
ACEGHLMPTY
K
1989.36
12.16
7
1
4
+6
5.53
-1.987
45.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
276.47
3
Residue Composition
number
0
A
3
R
1
N
1
D
0
C
0
E
1
Q
0
G
0
H
1
I
0
L
4
K
0
M
1
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 3 N: 1 D: 1 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 1 L: 0 K: 4 M: 0 F: 1 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
15
C89H149N31O21
1989.36
12.16
+6
5.53
-1.987
Amidation
L
Linear
Maleimide addition
N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Murine taile fibroblast (MTF) cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060035815

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Nucleic acid (siRNA)
In vitro
CCTTCTTTSCSCCCC
Additional Detail Fields 1 fields
CCTTCTTTSCSCCCC