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Peptide record

TPDB64004

No.63 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB64004
No.63
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Conjugation with fluorescein
Sequence
RTLVNEYKNTLKFSK
Physicochemical Analysis
C83H137N23O24
ADCQGHIMPW
K
1841.14
10.46
4
1
5
+3
3.93
-1.040
71.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
80.93
6
Residue Composition
number
0
A
1
R
2
N
0
D
0
C
1
E
0
Q
0
G
0
H
0
I
2
L
3
K
0
M
1
F
0
P
1
S
2
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 2 D: 0 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 3 M: 0 F: 1 P: 0 S: 1 T: 2 W: 0 Y: 1 V: 1
Chemical Descriptors
15
C83H137N23O24
1841.14
10.46
+3
3.93
-1.040
Free
L
Amphipathic
Linear
Conjugation with fluorescein
N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa, Jurkat and CHO

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Amphipathic
Synthetic
Fluorophore (fluorescein)
Similar or greater than TAT in CHO cells
In vitro
CCTHHHHTTSCSSCC
Additional Detail Fields 1 fields
CCTHHHHTTSCSSCC