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Peptide record

TPDB64003

Inv4 Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB64003
Inv4
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 23-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CPPsite3.0, MLCPP 2.0, and other sources, with an available 3D structural model.
N-terminal: Free (peptide coated FITC labelled microspheres)
Sequence
RSVTTEINTLFQTLTSIAEKVDP
Physicochemical Analysis
C112H187N29O39
CGHMWY
T
2563.89
4.44
2
3
8
-1
6.58
-0.130
97.39
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
9
Residue Composition
number
1
A
1
R
1
N
1
D
0
C
2
E
1
Q
0
G
0
H
2
I
2
L
1
K
0
M
1
F
1
P
2
S
5
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 1 N: 1 D: 1 C: 0 E: 2 Q: 1 G: 0 H: 0 I: 2 L: 2 K: 1 M: 0 F: 1 P: 1 S: 2 T: 5 W: 0 Y: 0 V: 2
Chemical Descriptors
23
C112H187N29O39
2563.89
4.44
-1
6.58
-0.130
Free
L
Linear
Free (peptide coated FITC labelled microspheres)
N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)N[C@@H](CCC(=O)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC(=O)O)C(=O)N1CCC[C@H]1C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Protein derived
Nanoparticle [(FITC)-labeled latex microspheres]
Cytoplasm and nucleus membrane
Low (relative to Inv3)
In vitro
CCSSCCHHHHHHHHHTTTTTCCC
Additional Detail Fields 1 fields
CCSSCCHHHHHHHHHTTTTTCCC