Back to search

Peptide record

TPDB64002

hAP10 DR (RT33 DR) Cell-penetrating Peptides modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.

Sequence-matched coordinates; source-recorded chemical modifications are not verified in this model.

TPDB64002
hAP10 DR (RT33 DR)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 10-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with FITC
Sequence
RSRSRRRRRK
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
10 main sequence record
Free Activity
L Activity
Cationic Activity
Linear Activity
Conjugated with FITC Activity
N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CS)C(=O)NCC(=O)O Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U2Os And C8161 Cancer Cells

Assay & Model

HUT78 Sézary bearing NOD/SCID gamma (NSG) mice
HUT78 Sézary bearing NOD/SCID gamma (NSG) mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
FITC dye , EGFP and survival protein AAC-11
Internalized approximately twice as more efficiently than hAP10 and about 50% more than TAT
Macropinocytosis
In vitro and in vivo
CCCCTTSSCC
Additional Detail Fields 1 fields
CCCCTTSSCC