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Peptide record

TPDB64001

hAP10 (RT33) Cell-penetrating Peptides modified_plain modified
10 amino acids
Basic Information
3D PDB MODEL
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Sequence-matched coordinates; source-recorded chemical modifications are not verified in this model.

TPDB64001
hAP10 (RT33)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 10-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Conjugated with FITC
Sequence
RSRSRDRRRK
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
10 main sequence record
Free Activity
L Activity
Cationic Activity
Linear Activity
Conjugated with FITC Activity
N[C@@H](CCCCN)C(=O)N[C@@H](CS)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](CS)C(=O)NCC(=O)O Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

U2Os And C8161 Cancer Cells Mrc-5 Cells

Assay & Model

HUT78 Sézary bearing NOD/SCID gamma (NSG) mice
HUT78 Sézary bearing NOD/SCID gamma (NSG) mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
FITC dye , EGFP and survival protein AAC-11
Similar uptake efficiency to that of penetratin
Macropinocytosis
In vitro and in vivo
CCCCCSSSCC
Additional Detail Fields 1 fields
CCCCCSSSCC