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Peptide record

TPDB63988

Mn1-RW9 Cell-penetrating Peptides standard
10 amino acids
Basic Information
3D PDB MODEL
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TPDB63988
Mn1-RW9
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 10-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RRWWWRRWRR
Physicochemical Analysis
C80H114N32O11
ANDCEQGHILKMFPSTYV
R
1699.99
13.10
6
0
4
+6
-2.54
-3.060
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
22000
1294.12
0
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
4
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 4 Y: 0 V: 0
Chemical Descriptors
10
C80H114N32O11
1699.99
13.10
+6
-2.54
-3.060
Free
L
Cationic and hydrophobic
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Ht29-Md2 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic and hydrophobic
Synthetic
Superoxide dismutases mimic (Mn1)
Cell Periphery
(Mn1-R9 < Mn1-MPP < Mn1-RW9 < Mn1), Mn content accumulated was 0.99 nmol.mg-1.
In vitro
CCCCCCCC
Additional Detail Fields 1 fields
CCCCCCCC