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Peptide record

TPDB63979

C2-P1 Cell-penetrating Peptides standard
21 amino acids
Basic Information
3D PDB MODEL
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TPDB63979
C2-P1
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 21-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: IMT-P8 (C2) at N terminus
Sequence
RRWRRWNRFNRRRCREEMQRR
Physicochemical Analysis
C128H211N59O29S2
ADGHILKPSTYV
R
3104.58
12.64
11
2
4
+9
9.07
-2.933
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
354.32
4
Residue Composition
number
0
A
11
R
2
N
0
D
1
C
2
E
1
Q
0
G
0
H
0
I
0
L
0
K
1
M
1
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 11 N: 2 D: 0 C: 1 E: 2 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 0 M: 1 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
21
C128H211N59O29S2
3104.58
12.64
+9
9.07
-2.933
Free
IMT-P8 (C2) at N terminus
L
Linear
Free
N[C@@H]([C@@H](C)O)C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CC(=O)N)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C(C)C)C(=O)NCC(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCSC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CO)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

PC-12 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
SNARE motif of VAMP2-patterned peptide
In vitro
CTTTTSSSCCSSCC
Additional Detail Fields 1 fields
CTTTTSSSCCSSCC