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Peptide record

TPDB63973

StAx Cell-penetrating Peptides modified_plain modified
17 amino acids
Basic Information
3D PDB MODEL
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TPDB63973
StAx
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 17-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Modified, details unspecified
Sequence
RRWPRXILDXHVRRVWR
Physicochemical Analysis
C95H153N37O18
ANCEQGKMFSTY
R
2101.50
12.70
7
1
6
+5
3.07
-1.200
80.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
11000
523.44
0
Residue Composition
number
0
A
6
R
0
N
1
D
0
C
0
E
0
Q
0
G
1
H
1
I
1
L
0
K
0
M
0
F
1
P
0
S
0
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 1 I: 1 L: 1 K: 0 M: 0 F: 0 P: 1 S: 0 T: 0 W: 2 Y: 0 V: 2
Chemical Descriptors
17
C95H153N37O18
2101.50
12.70
+5
3.07
-1.200
Free
Modified
Hydrophobic
Stapled
Free
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Non-natural residues Stapled Modified Hydrophobic
Synthetic
FITC-labeled
Cytosol, Nucleus and Endosomes
7-fold lower uptake than that of Pep-1 and SAHM1.
In vitro