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Peptide record

TPDB63969

P4 Cell-penetrating Peptides standard
15 amino acids
Basic Information
3D PDB MODEL
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TPDB63969
P4
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0 MLCPP 2.0 Peptipedia PerseuCPP
standard
No
A 15-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, MLCPP 2.0, Peptipedia, and other sources, with an available 3D structural model.
Chemical: Linker 6-aminohexamoic acid (Ahx) N-terminal: Conjugation with FITC
Sequence
RRVWRRYRRQRWCRR
Physicochemical Analysis
C98H161N45O18S1
ANDEGHILKMFPST
R
2289.71
12.70
9
0
4
+9
3.06
-2.693
19.33
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
12490
545.48
3
Residue Composition
number
0
A
9
R
0
N
0
D
1
C
0
E
1
Q
0
G
0
H
0
I
0
L
0
K
0
M
0
F
0
P
0
S
0
T
2
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 9 N: 0 D: 0 C: 1 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 0 P: 0 S: 0 T: 0 W: 2 Y: 1 V: 1
Chemical Descriptors
15
C98H161N45O18S1
2289.71
12.70
+9
3.06
-2.693
Free
Linker 6-aminohexamoic acid (Ahx)
L
Cationic
Linear
Conjugation with FITC
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Fluorophore (FITC)
Punctate cytoplasmic
Medium (compare to Tat)
In vitro
CTTHHHHHHHHSSCC
Additional Detail Fields 1 fields
CTTHHHHHHHHSSCC