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Peptide record

TPDB63968

Erns4 Cell-penetrating Peptides standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB63968
Erns4
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD CellPPD-MOD CPPsite3.0 Peptipedia PerseuCPP
standard
No
A 23-aa standard natural cell-penetrating peptides peptide sequence curated from CellPPD, CellPPD-MOD, CPPsite3.0, and other sources, with an available 3D structural model.
C-terminal: Amidation N-terminal: Biotinylation
Sequence
RRVTSWLGRQLRIAGKRLEGRSK-NH2
Physicochemical Analysis
C117H207N45O30
NDCHMFPY
R
2724.21
12.71
8
1
7
+7
5.93
-1.057
84.78
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
201.89
4
Residue Composition
number
1
A
6
R
0
N
0
D
0
C
1
E
1
Q
3
G
0
H
1
I
3
L
2
K
0
M
0
F
0
P
2
S
1
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 6 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 3 H: 0 I: 1 L: 3 K: 2 M: 0 F: 0 P: 0 S: 2 T: 1 W: 1 Y: 0 V: 1
Chemical Descriptors
23
C117H207N45O30
2724.21
12.71
+7
5.93
-1.057
Amidation
L
Cationic
Linear
Biotinylation
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)O)C(=O)N[C@@H](CO)C(=O)N[C@@H](CC1=C(C(=NC1)C)CC)C(=O)N[C@@H](CC(C)C)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](C)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCC(=O)O)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

EBTr cells

Source & Reference

CPPsite3.0
CPPsite3
US 20060223752

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Protein derived
Biotin
In vitro
CCGGGTHHHHTCSSCSSCCCSCC
Additional Detail Fields 1 fields
CCGGGTHHHHTCSSCSSCCCSCC