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Peptide record

TPDB63967

CUPID Cell-penetrating Peptides standard
16 amino acids
Basic Information
3D PDB MODEL
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TPDB63967
CUPID
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 16-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RRVQIWFQNKRAKVKR
Physicochemical Analysis
C95H161N35O20
DCEGHLMPSTY
R
2113.55
12.88
7
0
6
+7
4.47
-1.475
66.88
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
260.23
3
Residue Composition
number
1
A
4
R
1
N
0
D
0
C
0
E
2
Q
0
G
0
H
1
I
0
L
3
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 4 N: 1 D: 0 C: 0 E: 0 Q: 2 G: 0 H: 0 I: 1 L: 0 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
16
C95H161N35O20
2113.55
12.88
+7
4.47
-1.475
Free
L
Hydrophobic
Linear
Free
N[C@@H](CC(C)C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](Cc1[nH]cnc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CC1=NC=NC1)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

E. Coli , C. Crescentus Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Hydrophobic
Protein derived
SpyCatcher003 at C-terminus of CPP via GGGS spacer
Cytoplasm
CUPID produced a slight increase in uptake of the fusion protein of the SpyCatcher alone conditions.
In vitro
CCSSCGGGHHHHSCCC
Additional Detail Fields 1 fields
CCSSCGGGHHHHSCCC