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Peptide record

TPDB63940

fusion peptide (P) Cell-penetrating Peptides standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB63940
fusion peptide (P)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 18-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RRRRRRRRRRHVLPKVQA
Physicochemical Analysis
C101H190N52O20
NDCEGIMFSTWY
R
2452.96
13.36
12
0
4
+11
10.49
-2.400
59.44
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
10
R
0
N
0
D
0
C
0
E
1
Q
0
G
1
H
0
I
1
L
1
K
0
M
0
F
1
P
0
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 10 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 1 I: 0 L: 1 K: 1 M: 0 F: 0 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
18
C101H190N52O20
2452.96
13.36
+11
10.49
-2.400
Free
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa Cells

Assay & Model

Drosophila melanogaster wild-type strain Canton S and two transgenic lines
Drosophila melanogaster wild-type strain Canton S and two transgenic lines

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Fusogenic
Cyclometalated Pt(II) complexes (Pt1, Pt2 and Pt3)
Cytoplasm
In vitro and in vivo
CCCCTTCC
Additional Detail Fields 1 fields
CCCCTTCC