Peptide record

TPDB63932

R9-BP100 Cell-penetrating Peptides standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB63932
R9-BP100
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 20-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: Nanoparticles
Sequence
RRRRRRRRRKKLFKKILKYL
Physicochemical Analysis
C126H232N52O22
ANDCEQGHMPSTWV
R
2827.56
12.95
14
0
6
+14
8.18
-2.130
78.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
52.70
1
Residue Composition
number
0
A
9
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
3
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 9 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 3 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
20
C126H232N52O22
2827.56
12.95
+14
8.18
-2.130
Free
Nanoparticles
L
Cationic
Linear
Free
N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Arabidopsis Thaliana (Arabidopsis Ecotype Col-0) , Soybean (Glycine Max) And Tomato (Solanum Lycopersicum)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Fusogenic
Cyanine 3 (Cy3)-labeled pBI221
Cytoplasm
2- to 5-fold stronger Cy3 fluorescent signals were observed in epidermal cells of Arabidopsis sprayed with all four Cy3-labeled pBI221/BP100-derived cationic CPP complexes than Cy3-labeled pBI221 only and Cy3-labeled pBI221/BP100.
In vitro
CTTHHHHHHHHHHHTTCCCC
Additional Detail Fields 1 fields
CTTHHHHHHHHHHHTTCCCC