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Peptide record

TPDB63927

R9-GFP11 Cell-penetrating Peptides standard
29 amino acids
Basic Information
3D PDB MODEL
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TPDB63927
R9-GFP11
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 29-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RRRRRRRRRGSGSRDHMVLHEYVNAAGIT
Physicochemical Analysis
C143H248N64O39S1
CQKFPW
R
3520.01
12.58
12
2
8
+8
11.88
-1.534
53.79
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
42.33
5
Residue Composition
number
2
A
10
R
1
N
1
D
0
C
1
E
0
Q
3
G
2
H
1
I
1
L
0
K
1
M
0
F
0
P
2
S
1
T
0
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 10 N: 1 D: 1 C: 0 E: 1 Q: 0 G: 3 H: 2 I: 1 L: 1 K: 0 M: 1 F: 0 P: 0 S: 2 T: 1 W: 0 Y: 1 V: 2
Chemical Descriptors
29
C143H248N64O39S1
3520.01
12.58
+8
11.88
-1.534
Free
L
Cationic
Linear
Free
N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](CO)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

N. Benthamiana And A. Thaliana

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Chimeric
GFP11 peptide and AtWUS factor
Cytoplasm And Nucleolar
High delivery efficiency (>40% positive)
Direct membrane translocation and Endocytosis
In vitro
CCCCCCCCCCCCTTSSTTCCCSCSSSCCSCCC
Additional Detail Fields 1 fields
CCCCCCCCCCCCTTSSTTCCCSCSSSCCSCCC