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Peptide record

TPDB63901

SP2-332/348 LA (Octaarginine , R8) Cell-penetrating Peptides standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB63901
SP2-332/348 LA (Octaarginine , R8)
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 27-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RRRRRRRRGGWPVIAKPKKAPKPPAKL
Physicochemical Analysis
C144H255N57O28
NDCEQHMFSTY
R
3232.97
13.25
13
0
7
+13
10.54
-1.752
50.74
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
170.12
0
Residue Composition
number
3
A
8
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
1
I
1
L
5
K
0
M
0
F
5
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 8 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 1 K: 5 M: 0 F: 0 P: 5 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
27
C144H255N57O28
3232.97
13.25
+13
10.54
-1.752
Free
L
Linear
Free
N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)NCC(=O)NCC(=O)N[C@@H](CC1=CN=C(C)/C/1=C\C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N.CN.C.C.C.CC(=O)N[C@@H](C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CC(C)C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Jurkat Cells And El-4 Cells

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
In vitro
CCCCCCCCCCCCSSCCCCCSSSSCSCC
Additional Detail Fields 1 fields
CCCCCCCCCCCCSSCCCCCSSSSCSCC