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Peptide record

TPDB63893

CPPs-GLP-2 Cell-penetrating Peptides standard
43 amino acids
Basic Information
3D PDB MODEL
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TPDB63893
CPPs-GLP-2
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 43-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RRRRRRRRGGHADGSFSDEMNTILDNLAARDFINWLIQTKITD
Physicochemical Analysis
C217H356N78O65S1
CPYV
R
5129.76
11.87
11
6
14
+4
12.19
-1.072
70.47
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
107.22
9
Residue Composition
number
3
A
9
R
3
N
5
D
0
C
1
E
1
Q
3
G
1
H
4
I
3
L
1
K
1
M
2
F
0
P
2
S
3
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 9 N: 3 D: 5 C: 0 E: 1 Q: 1 G: 3 H: 1 I: 4 L: 3 K: 1 M: 1 F: 2 P: 0 S: 2 T: 3 W: 1 Y: 0 V: 0
Chemical Descriptors
43
C217H356N78O65S1
5129.76
11.87
+4
12.19
-1.072
Free
L
Linear
Free
N[C@@H](CS)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CC(=O)O)C(=O)NCC(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Assay & Model

5-to 7-week-old male ddY mice
5-to 7-week-old male ddY mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
Fluorescein isothiocyanate (FITC)-labeled
CPPs-GLP-2 was not able to cross the BBB
Macropinocytosis
In vivo
CCCCTTTTSSCC
Additional Detail Fields 1 fields
CCCCTTTTSSCC