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Peptide record

TPDB63892

PTD-DBM Cell-penetrating Peptides standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB63892
PTD-DBM
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 26-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Conjugated with FITC
Sequence
RRRRRRRRGGGGRKTGHQICKFRKCK
Physicochemical Analysis
C130H237N63O29S2
ANDELMPSWYV
R
3210.84
12.77
15
0
2
+14
11.87
-2.219
15.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
125
3.89
4
Residue Composition
number
0
A
10
R
0
N
0
D
2
C
0
E
1
Q
5
G
1
H
1
I
0
L
4
K
0
M
1
F
0
P
0
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 10 N: 0 D: 0 C: 2 E: 0 Q: 1 G: 5 H: 1 I: 1 L: 0 K: 4 M: 0 F: 1 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
26
C130H237N63O29S2
3210.84
12.77
+14
11.87
-2.219
Conjugated with FITC
L
Linear
Free
N[C@@H](Cc1ccccc1)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Human Dermal Fibroblasts And Hacat Keratinocytes

Assay & Model

7-wk-old male C3H mice
7-wk-old male C3H mice

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Chimeric
Dvl-binding motif (DBM)
Nucleus
In vitro and in vivo
CCBTTTBCSCC
Additional Detail Fields 1 fields
CCBTTTBCSCC