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Peptide record

TPDB63859

Cell-penetrating Peptides standard
14 amino acids
Basic Information
3D PDB MODEL
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TPDB63859
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 14-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RRRRRFDLWKLLEN
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C87H144N32O20
ACQGHIMPSTYV
R
1958.30
12.23
6
2
5
+4
5.87
-1.686
83.57
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
2.81
1
Residue Composition
number
0
A
5
R
1
N
1
D
0
C
1
E
0
Q
0
G
0
H
0
I
3
L
1
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 5 N: 1 D: 1 C: 0 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 3 K: 1 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
14 reviewed residue count
C87H144N32O20 sequence-only estimate (linear, free termini)
1958.30 sequence-only estimate (linear, free termini)
12.23 sequence-only estimate (linear, free termini)
+4 sequence-only estimate (linear, free termini)
5.87 sequence-only estimate (linear, free termini)
-1.686 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.