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Peptide record

TPDB63840

Cell-penetrating Peptides standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB63840
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 17-aa standard-residue cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Sequence
RRRQRRKKRSARGFWFG
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C98H162N42O20
NDCEHILMPTYV
R
2248.63
13.18
9
0
4
+9
6.62
-2.229
5.88
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
5500
2.45
2
Residue Composition
number
1
A
7
R
0
N
0
D
0
C
0
E
1
Q
2
G
0
H
0
I
0
L
2
K
0
M
2
F
0
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 7 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 0 L: 0 K: 2 M: 0 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
17 reviewed residue count
C98H162N42O20 sequence-only estimate (linear, free termini)
2248.63 sequence-only estimate (linear, free termini)
13.18 sequence-only estimate (linear, free termini)
+9 sequence-only estimate (linear, free termini)
6.62 sequence-only estimate (linear, free termini)
-2.229 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.