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Peptide record

TPDB63829

scrambled peptide 16 Cell-penetrating Peptides modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
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Standard-residue backbone model; source-recorded chemical modifications are not verified in these coordinates.

TPDB63829
scrambled peptide 16
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 14-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
C-terminal: Amidation N-terminal: Conjugated with 5-Thio-2-Nitrobenzoic Acid-Disulfide (Tnb)
Sequence
RRRIRFRRRLRRRF-NH2
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
14 reviewed residue count
Amidation Activity
L Activity
Linear Activity
Conjugated with 5-Thio-2-Nitrobenzoic Acid-Disulfide (Tnb) Activity
N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)O Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

HeLa And Hek293T

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L
Synthetic
Protein congugate I (NLS-mCherry-R10),Protein congugate II(NLS-mCherry-SS-R10) ,Protein congugate III (NLS-mCherry-SS-cR10) and protein conjugate IV (NLS-mCherry-R10-ILFF)
Cytosol And Nucleolar
HeLa cells cotreated with I and 16 did not show any nucleolar staining.
Endocytosis
In vitro
CTTC
Additional Detail Fields 1 fields
CTTC