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Peptide record

TPDB63826

Stearyl-R3H5 Cell-penetrating Peptides modified_plain modified
8 amino acids
Basic Information
3D PDB MODEL
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Standard-residue backbone model; source-recorded chemical modifications are not verified in these coordinates.

TPDB63826
Stearyl-R3H5
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
modified_plain
Yes
A 8-aa modified cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
N-terminal: Stearylation
Sequence
RRRHHHHH
Physicochemical Analysis

Sequence-only estimates are not provided for modified or non-standard source notation. Reported molecular properties, when available, are retained below with their source records.

Chemical Descriptors
8 reviewed residue count
Free Activity
L Activity
Cationic Activity
Linear Activity
Stearylation Activity
NCC(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCC(=O)N)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)N[C@@H](CCCN=C)C(=O)O Activity
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Scl-1 Cells

Assay & Model

SCL-1 tumor bearing Nude mice (BALB/c-nu, female, 4–5 weeks old)
SCL-1 tumor bearing Nude mice (BALB/c-nu, female, 4–5 weeks old)

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Linear L Cationic
Synthetic
Lycorine-oleic acid ionic complex (LR-OA)
CPP-modifed C6-loaded transfersomes exhibited stronger intracellular green fuorescence intensity than unmodifed C6-loaded transfersomes,
Endocytosis
In vitro and in vivo
CCCCCCTTCC
Additional Detail Fields 1 fields
CCCCCCTTCC