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Peptide record

TPDB63825

Cell-penetrating Peptides standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB63825
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CellPPD-MOD CPPsite3.0 Peptipedia
standard
No
A 9-aa standard-residue cell-penetrating peptides peptide sequence curated from CellPPD-MOD, CPPsite3.0, and Peptipedia, with an available 3D structural model.
Sequence
RRRGRKKRR
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C50H101N29O10
ANDCEQHILMFPSTWYV
R
1268.54
13.10
8
0
0
+8
11.08
-3.911
0.00
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
6
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
0
I
0
L
2
K
0
M
0
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 0 L: 0 K: 2 M: 0 F: 0 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
9 reviewed residue count
C50H101N29O10 sequence-only estimate (linear, free termini)
1268.54 sequence-only estimate (linear, free termini)
13.10 sequence-only estimate (linear, free termini)
+8 sequence-only estimate (linear, free termini)
11.08 sequence-only estimate (linear, free termini)
-3.911 sequence-only estimate (linear, free termini)
Evidence Records 1 records
Evidence 1 Activity

Source & Reference

CPPsite3.0

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.