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Peptide record

TPDB63808

DRx-170 Cell-penetrating Peptides standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB63808
DRx-170
Cell-penetrating Peptides
Delivery and barrier-penetrating peptides
CPPsite3.0
standard
No
A 12-aa standard natural cell-penetrating peptides peptide sequence curated from CPPsite3.0, with an available 3D structural model.
Chemical: FITC-labelled
Sequence
RRLSGNEYVLST
Physicochemical Analysis
C59H99N19O20
ADCQHIKMFPW
RLS
1394.55
9.87
2
1
4
+1
2.48
-0.683
89.17
Mammalian: 1 hour Yeast: 2 min E.coli: 2 min
1490
106.84
5
Residue Composition
number
0
A
2
R
1
N
0
D
0
C
1
E
0
Q
1
G
0
H
0
I
2
L
0
K
0
M
0
F
0
P
2
S
1
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 1 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 0 L: 2 K: 0 M: 0 F: 0 P: 0 S: 2 T: 1 W: 0 Y: 1 V: 1
Chemical Descriptors
12
C59H99N19O20
1394.55
9.87
+1
2.48
-0.683
Free
FITC-labelled
L
Cyclic
Free
N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCN=C)C(=O)O
Evidence Records 1 records
Evidence 1 Activity

Activity

Cell-penetrating Peptides

Target

Panc1 Cell Line

Source & Reference

CPPsite3.0
CPPsite3

Other

Source Activity Label Source Definition
Cell-penetrating Peptides
CPPsite3.0 experimentally validated cell-penetrating peptide annotation.
Natural residues Cyclic L
Protein derived
Afatinib
Cytoplasm and Nuclei
DRx-170 readily gains intracellular access
In vitro
CCSCC
Additional Detail Fields 1 fields
CCSCC